ENGLEWOOD – The Broncos on Friday ruled out linebacker Dre Greenlaw for Sunday’s regular-season finale against the Los Angeles Chargers at Empower Field at Mile High.

Greenlaw, who hurt his hamstring late in a 34-20 loss to Jacksonville on Dec. 21, will miss his second straight game. He has not practiced since the injury.

The Broncos listed defensive lineman John Franklin-Myers as questionable for Sunday with a hip injury. Franklin-Myers got in for just 11 snaps in their 20-13 win at Kansas City on Dec. 25 due to the injury and was limited all week in practice.

Wide receiver Pat Bryant (concussion) and tight end Nate Adkins (knee) both have no injury designation after sitting out against the Chiefs.

Denver also announced that rookie linebacker Karene Reid, who was designated for return from injured reserve Dec. 17, will not be activated for Sunday’s game. It will be the seventh straight game missed by Reid, who had a hamstring injury. The Broncos will need to decide by Tuesday whether to activate Reid or shelve him for the playoffs.

The Chargers plan to rest some starters, including starting quarterback Justin Herbert, on Sunday, as they have already clinched a playoff berth and know they will open the postseason on the road. Star linebacker Khalil Mack, like Herbert, didn’t practice Friday and could be a candidate to also sit out.

The Chargers on their injury report Friday officially listed running back Omarion Hampton (concussion), cornerback Nikko Reed (hamstring) as out, defensive back Elijah Molden (hamstring) and offensive lineman Jamaree Salyer (hamstring) as doubtful and center Bradley Bozeman (concussion), running backs Hassan Haskins (concussion) and Kimani Vidal (neck), safety R.J. Mickens (shoulder) and cornerback Benjamin St-Juste (shoulder) as questionable.